LEECH MANAGEMENT BEFORE APPLICATION ON PATIENT: A NATIONWIDE SURVEY OF PRACTICES IN FRENCH UNIVERSITY HOSPITALS

Leech management before application on patient: a nationwide survey of practices in French university hospitals

Abstract Background Leech therapy in plastic/reconstructive microsurgery significantly improves a successful outcome of flap salvage but the drawback is a risk of severe infection that results in a drop of the salvage rates from 70-80% to below 30%.We report the results of a national survey Control Link conducted in all the French university hospit

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Unveiling the mechanistic link between extracellular amyloid fibrils, mechano-signaling and YAP activation in cancer

Abstract The tumor microenvironment is a complex ecosystem that plays a critical role in cancer progression and treatment response.Recently, extracellular amyloid fibrils have emerged as novel components of the tumor microenvironment; however, their function remains elusive.In this study, we establish a direct connection between the presence of amy

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